Glycine Benefits: 7 Science-Backed Reasons to Take It (2026)

Last reviewed: June 1, 2026 · Reviewed by the YourHealthier Science Team · Editorial Policy

Glycine is the smallest amino acid in the human body, and one of the most underrated. It makes up a third of all collagen, acts as an inhibitory neurotransmitter in the brain, and participates in over a dozen metabolic pathways from antioxidant defense to blood sugar regulation. Yet most people have never heard of it as a standalone supplement.

That's changing. A 2024 systematic review in GeroScience, led by researchers at the University of Geneva's Department of Psychiatry, analyzed 50 human studies across 11 physiological systems and found that glycine supplementation produced the most consistently positive outcomes in the nervous system — particularly for sleep quality and cognition (Soto-Diaz et al., 2024). A separate 2024 review in Nutrients confirmed that 3 grams of glycine before bedtime improves both subjective and objective sleep measures in multiple trials (Inose et al., 2024).

This article covers seven evidence-backed benefits of glycine, the research behind each, what dose actually works, the best food sources, and how glycine connects to magnesium glycinate, the supplement form many people are already taking without realizing they're getting glycine too.

1. Sleep Quality: The Strongest Evidence

Sleep is where glycine's evidence is most consistent and well-replicated. Multiple randomized controlled trials have demonstrated that 3 grams of glycine taken before bedtime improves sleep quality without the side effects associated with pharmaceutical sleep aids.

Here is how it works. Glycine binds to NMDA receptors in the suprachiasmatic nucleus, the brain's master clock, triggering a drop in core body temperature. This temperature decrease is one of the key physiological signals that initiates sleep. Unlike benzodiazepines or antihistamine sleep aids, glycine doesn't alter normal sleep architecture; it appears to improve the quality of each sleep stage rather than forcing sedation (Kawai et al., 2015, Neuropsychopharmacology).

Several controlled trials back this up. Yamadera et al. (2007) conducted a placebo-controlled crossover study showing that 3g of glycine before bed significantly improved subjective sleep quality and reduced daytime sleepiness in participants with sleep complaints. A separate trial by Bannai et al. (2012) confirmed these findings using polysomnography — the gold standard for measuring sleep objectively, and demonstrated that glycine reduced the time to reach slow-wave sleep without affecting total sleep time.

Inose et al. published a systematic review in Nutrients (2024) that synthesized the available data and concluded that glycine supplementation improves subjective sleep quality, reduces sleep onset latency, and improves next-day alertness in individuals with insufficient sleep (Inose et al., 2024). The review noted that most studies used 3g as the standard dose, taken approximately 1 hour before bedtime.

For context on how glycine compares to other sleep-supporting supplements: it works through a different mechanism than magnesium glycinate (which acts on GABA receptors) or ashwagandha (which lowers cortisol). This makes them potentially complementary rather than redundant, a point we'll return to in the dosage section.

2. Collagen Synthesis and Joint Health

Glycine is the most abundant amino acid in collagen — the structural protein that holds together skin, joints, tendons, bones, and blood vessels. About one-third of every collagen molecule is glycine, arranged in the characteristic Gly-X-Y repeating pattern that gives collagen its triple-helix structure.

Here's the problem: your body doesn't make enough glycine to keep up with demand. According to research by Enrique Meléndez-Hevia, a biochemistry professor at the University of La Laguna (Spain), the metabolic capacity for glycine biosynthesis falls significantly short of what's needed for optimal collagen synthesis and other glycine-dependent functions. His team calculated that the estimated shortfall is approximately 10g/day beyond what the body produces and what a typical diet provides, making glycine functionally "conditionally essential" despite being classified as non-essential (Meléndez-Hevia et al., 2009, Journal of Biosciences).

This matters as you age. Collagen production naturally declines starting around age 25, accelerating after 40. If glycine is already the limiting factor in collagen synthesis, and the data suggests it is — then a chronic glycine shortfall compounds the age-related decline. Supplementing with glycine or collagen peptides (which are ~33% glycine by weight) may help close this gap.

A 2025 clinical trial published in npj Aging found that supplementation with a collagen amino acid composition, in which glycine, proline, and hydroxyproline were present in collagen's natural 3:1:1 ratio, improved skin features within 3 months and reduced biological age by 1.4 years (p = 0.04) within 6 months in human participants. The researchers identified glycine as a key active component of this effect.

If you're already taking a collagen supplement, you're getting glycine. If you're taking magnesium glycinate, you're getting a smaller but meaningful glycine dose (about 1.4g per standard serving) as a secondary benefit.

3. Anti-Inflammatory and Antioxidant Effects

Glycine has direct anti-inflammatory properties that go beyond its role as a building block. It modulates the production of pro-inflammatory cytokines — including TNF-alpha and IL-6, and serves as a precursor to glutathione, the body's primary endogenous antioxidant.

A 2023 comprehensive review in the International Journal of Molecular Sciences described glycine as "the smallest amino acid with big impact" and detailed its cytoprotective effects across multiple organ systems: liver, kidney, cardiovascular, and immune (Aguayo-Cerón et al., 2023). The review highlighted glycine's ability to suppress activation of NF-κB, a master regulator of inflammatory gene expression — and reduce oxidative stress markers in both animal and human studies.

Soto-Diaz et al.'s 50-study review noted that glycine supplementation in diabetic patients reduced markers of oxidative stress and inflammation, with effects seen at doses of 5–15g/day over 3 months (Soto-Diaz et al., 2024). The glutathione connection is particularly relevant: glycine is one of three amino acids (along with cysteine and glutamic acid) required to synthesize glutathione. In people with low glycine intake, glutathione production may be impaired, contributing to elevated oxidative stress and chronic low-grade inflammation.

Related reading on inflammation management through diet and supplements, see our articles on ashwagandha and cortisol and berberine benefits.

4. Blood Sugar Regulation

Blood sugar regulation is another area where glycine shows promise, working through mechanisms that don't overlap with insulin or metformin.

Research shows that glycine stimulates glucagon-like peptide-1 (GLP-1) secretion and improves the insulin response to glucose. In studies of patients with type 2 diabetes, supplementing with 5g of glycine before meals reduced post-meal blood sugar spikes. At higher doses (15g/day for 3 months), glycine supplementation decreased glycosylated hemoglobin (HbA1c), a key long-term blood sugar marker — in diabetic patients (Soto-Diaz et al., 2024).

A 2024 review in Sports confirmed glycine's role in glucose regulation and also noted its potential to improve insulin sensitivity through anti-inflammatory mechanisms (Ramos-Jiménez et al., 2024). For people interested in blood sugar management, see our article on berberine dosage, which covers a supplement with stronger and more extensive evidence for glycemic control.

5. Muscle Preservation and Recovery

Glycine plays a direct role in muscle protein synthesis and has shown protective effects against muscle wasting in both preclinical and clinical studies.

A 2024 review in Sports by Ramos-Jiménez et al. examined glycine's potential as an ergogenic aid and found that it activates anabolic pathways (mTOR signaling) while inhibiting proteolytic gene expression, meaning it may simultaneously promote muscle building and prevent muscle breakdown. Animal studies have demonstrated that glycine supplementation preserves muscle mass during caloric restriction and aging (Ramos-Jiménez et al., 2024).

In human studies, the evidence is earlier-stage but encouraging. Glycine supplementation has been shown to enhance peak power output and reduce lactic acid accumulation during high-intensity exercise in some trials. The authors concluded that glycine represents a "promising" but not yet proven ergogenic nutrient, and called for larger human trials to confirm the muscle-specific benefits.

Athletes and fitness enthusiasts may find glycine complements creatine (which glycine also helps synthesize) and magnesium (which supports muscle relaxation and recovery). For more on this connection, see our article on when to take creatine.

6. Neuroprotection and Cognitive Support

Beyond sleep, glycine's role as an inhibitory neurotransmitter gives it broader relevance to brain health. In the central nervous system, glycine acts alongside GABA to modulate neural excitability, essentially helping to calm overactive neural circuits.

The GeroScience systematic review found that the nervous system showed the most consistently positive outcomes from glycine supplementation across all 11 physiological systems evaluated. Benefits included improved sleep quality, reduced fatigue, and enhanced cognitive function in healthy adults. The reviewers noted that oral glycine supplementation was confirmed to increase glycine levels in the brain in human subjects — a key prerequisite for central effects (Soto-Diaz et al., 2024).

For people interested in cognitive support, glycine is mechanistically distinct from lion's mane (which works through NGF) and NMN (which supports NAD+ levels). These different mechanisms make them potentially complementary rather than redundant.

Watch: A Doctor Explains Why He Takes Glycine Daily

Dr. Brad Stanfield, a registered General Practitioner in New Zealand and Fellow of the Royal New Zealand College of General Practitioners, explains the research that convinced him to add glycine to his daily supplement protocol, including the sleep, collagen, and longevity data:

7. The Magnesium Glycinate Connection

If you take magnesium glycinate, you're already getting glycine without realizing it — and this dual delivery may explain why many people report sleep and mood benefits beyond what they'd expect from magnesium alone.

Magnesium glycinate is magnesium chelated (bonded) to two glycine molecules. A standard dose providing 200mg of elemental magnesium delivers approximately 1.4g of glycine as part of the molecular complex. This means a typical magnesium glycinate supplement provides both magnesium's GABA-receptor benefits and glycine's NMDA-receptor sleep-promoting effects in a single capsule.

This dual mechanism may explain why magnesium glycinate consistently outperforms other magnesium forms (oxide, citrate, chloride) for sleep in anecdotal reports, and why the magnesium glycinate for sleep combination is so widely recommended by integrative practitioners. The magnesium relaxes muscles and activates GABA; the glycine lowers core body temperature and promotes slow-wave sleep. Two different sleep pathways from one supplement.

Still, a standard magnesium glycinate dose provides 1.4g of glycine, less than the 3g used in most sleep-specific glycine trials. People who want the full glycine benefit for sleep may need to supplement with additional standalone glycine or increase their magnesium glycinate dose (within safe limits). For dosing specifics, see our magnesium glycinate dosage guide.

Glycine Dosage: What the Research Supports

Dosing depends on the target benefit. Here's what clinical trials have used:

Benefit	Dose Used in Trials	Timing	Evidence Level
Sleep quality	3g/day	1 hour before bed	Strong (multiple RCTs)
Collagen support	5–10g/day	With meals	Moderate
Anti-inflammatory	5–15g/day	Divided with meals	Moderate (mostly diabetic populations)
Blood sugar	5g before meals / 15g/day	Before meals	Moderate
Muscle preservation	3–5g/day	Around exercise	Preliminary
Via magnesium glycinate	~1.4g (from standard Mg dose)	Evening	Strong for sleep (combined mechanism)

For sleep specifically, 3g is the well-studied dose. You can get this from standalone glycine powder (tasteless, dissolves in water) or from a combination of magnesium glycinate + additional glycine.

Best Food Sources of Glycine

The richest dietary sources of glycine are animal-derived proteins — particularly collagen-rich foods that most modern diets lack.

Food	Glycine per Serving	Notes
Bone broth (1 cup)	2.5–4.0g	Varies widely by preparation. Homemade > store-bought.
Pork skin / gelatin (1 oz)	3.0–3.5g	Highest concentration of any whole food.
Chicken skin (3 oz)	1.5–2.0g	Often discarded, a lost glycine source.
Collagen peptides (10g scoop)	~3.3g	Supplement form. ~33% glycine by weight.
Beef (3 oz)	1.0–1.5g	Muscle meat has less glycine than connective tissue.
Soybeans (1 cup cooked)	1.0g	Best plant source.
Spinach (1 cup cooked)	0.3g	Minor source. You'd need enormous quantities.

Notice the pattern: modern Western diets favor muscle meat over skin, bones, and connective tissue, exactly the glycine-rich parts that ancestral diets included naturally. This dietary shift is a major reason for the estimated ~7g/day glycine gap identified by Meléndez-Hevia (2009). For people who don't regularly consume bone broth, organ meats, or collagen, supplementation is the most practical way to close this gap.

How to Get Glycine: Source Comparison

There are three main ways to supplement glycine, each with different tradeoffs:

Source	Glycine per Serving	Cost/Serving	Best For
Standalone glycine powder	3g (1 tsp)	~$0.08	Sleep (3g before bed). Cheapest per gram. Tasteless, mixes in water.
Collagen peptides (10g scoop)	~3.3g	~$0.50–1.00	Skin/joint support + glycine. Provides proline and hydroxyproline too.
Magnesium glycinate (200mg Mg)	~1.4g	~$0.30–0.55	Sleep + magnesium benefits. Dual mechanism. Less glycine per serving.
Bone broth (1 cup)	2.5–4g	~$1.50–3.00	Whole-food approach. Variable glycine content. Also provides minerals.

For sleep specifically, standalone glycine powder at 3g/day is the most cost-effective option. If you want both magnesium and glycine benefits, magnesium glycinate delivers both in one supplement — though the glycine dose (1.4g) is below the 3g clinical threshold for standalone sleep effects. Combining magnesium glycinate with 1.5g of additional glycine powder bridges the gap.

What Most "Glycine Benefits" Articles Get Wrong

After reviewing the top 10 ranking articles for this keyword, three recurring problems stand out:

1. They overstate the evidence for benefits beyond sleep. Sleep is the only area with multiple well-controlled RCTs in healthy adults. Collagen support is based on strong biochemistry but fewer direct supplementation trials. Anti-inflammatory and blood sugar benefits come primarily from studies in diabetic populations, not healthy adults. Most articles present all benefits as equally well-supported, which isn't accurate.

2. They don't mention the glycine gap. Nearly every article lists glycine as "non-essential" without explaining that the body's synthesis capacity falls ~7g short of optimal daily needs. This distinction, between what the body can make and what it actually needs — is the entire rationale for supplementation. Without it, readers reasonably ask "why would I supplement something my body already makes?"

3. They don't connect glycine to magnesium glycinate. Millions of people take magnesium glycinate without realizing they're also getting glycine. Healthline's #4-ranking article doesn't mention this connection at all. If you're already getting 1.4g/day of glycine from your magnesium supplement, that changes the supplementation math.

Important Limitations

Glycine's evidence base is stronger than many supplement ingredients, but it has real limitations worth acknowledging:

Most sleep trials are small and industry-funded. Several key glycine-sleep studies were funded by Ajinomoto, a major amino acid manufacturer. While the results have been replicated by independent groups, the heavy industry involvement warrants awareness. Larger, independently funded trials would strengthen confidence.

Benefits beyond sleep have weaker direct evidence. Collagen synthesis, anti-inflammatory, and blood sugar benefits are supported by solid mechanistic data and some clinical trials, but most of those trials were conducted in specific populations (diabetic patients, menopausal women). Whether the same benefits apply to healthy young adults hasn't been established with the same rigor.

"Conditionally essential" is still debated. While Meléndez-Hevia's 2009 calculation of a glycine biosynthesis shortfall is widely cited, some researchers argue that the body adapts to lower glycine availability by prioritizing essential functions. The 10g/day "optimal need" figure is an estimate, not a hard threshold, and whether everyone below it is functionally deficient is unresolved.

Original Analysis: Evidence Quality by Benefit Category

We scored each glycine benefit against four criteria: number of human trials, total participants, replication by independent groups, and whether systematic reviews support the claim. This analysis isn't available in any competing article:

Benefit	Human Trials	Replicated?	Systematic Review?	Evidence Grade
Sleep quality	4+ RCTs	Yes (3+ groups)	Yes (Inose 2024)	Strong
Collagen synthesis	2–3 (mostly collagen peptide trials)	Partial	Indirect	Moderate
Anti-inflammatory	3–4 (mostly diabetic populations)	Yes	Yes (Soto-Diaz 2024)	Moderate
Blood sugar	3–4 (diabetic populations)	Yes	Yes (Soto-Diaz 2024)	Moderate
Muscle preservation	1–2 + preclinical	No	Narrative review only	Preliminary
Neuroprotection	Indirect (via sleep + anti-inflammatory)	N/A	Partial	Preliminary
Anti-aging/longevity	1 clinical trial (2025)	No	No	Very Preliminary

What matters here: Sleep is the one benefit you can recommend with real confidence. Everything else ranges from "promising" to "preliminary." That's not a reason to dismiss glycine — it's a reason to set expectations appropriately and prioritize it for what it does best.

Side Effects and Safety

Safety data is reassuring. Across 50 human studies reviewed by Soto-Diaz et al. (2024), no significant adverse effects were reported. Clinical trials have used doses up to 9g/day for sleep and up to 15g/day for metabolic benefits without serious side effects (Soto-Diaz et al., 2024). The 2024 Sports review noted that toxicity only appears at levels exceeding 500 mg/kg of body weight in preclinical models, a dose that would translate to over 35g for a 70kg adult and is essentially impossible to reach through normal supplementation (Ramos-Jiménez et al., 2024).

Mild GI discomfort has been reported in some trials at higher doses (>10g/day). Starting at 3g/day and increasing gradually is a reasonable approach. People with kidney disease should consult their doctor before supplementing, as the kidneys process excess amino acids. For broader safety context, see our article on magnesium glycinate side effects.

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How much glycine should I take before bed?

The Inagawa 2006 and Bannai 2012 studies used 3 grams of glycine taken approximately 1 hour before bedtime. This dose improved subjective sleep quality and reduced next-day fatigue. Magnesium glycinate provides some glycine as the chelation carrier, but typically delivers less than 1 gram of free glycine per serving.

Is glycine the same as magnesium glycinate?

No. Magnesium glycinate (bisglycinate) is magnesium chelated to two glycine molecules. The glycine serves as a carrier to improve magnesium absorption and adds a mild calming effect. Standalone glycine supplements provide free glycine at higher doses (3 g) for sleep-specific protocols. They are complementary, not identical. See magnesium glycinate benefits.

What's new in supplement research: 2025–2026

Several lines of supplement research converged in 2025–2026. Ashwagandha gained its first 12-month safety dataset (Salve et al., Phytotherapy Research, 191 participants on KSM-66). The NMN field saw NAD+ elevation confirmed across multiple dosing regimens, and creatine’s cognitive benefits attracted a fresh meta-analysis.

Glycine as a standalone supplement versus glycine from magnesium glycinate

An important distinction that most supplement guides conflate: the glycine you get from magnesium glycinate (bisglycinate) is not equivalent in dose to standalone glycine supplementation, and they serve overlapping but different purposes.

Magnesium bisglycinate is approximately 14% magnesium and 86% glycine by molecular weight. A standard dose of 2,000 mg magnesium bisglycinate delivers approximately 280 mg of elemental magnesium and 1,720 mg of glycine. The glycine in this context serves primarily as a chelation carrier to improve magnesium absorption, and the amount delivered (1.7 g) is below the 3 grams used in the standalone glycine sleep studies (Inagawa 2006, Bannai 2012).

Standalone glycine supplementation at 3 grams before bed targets a different primary mechanism: glycine acts directly on NMDA receptors in the suprachiasmatic nucleus, lowering core body temperature and facilitating sleep onset. This is independent of the GABA-modulating effect of the magnesium ion. The Inagawa study found that 3 grams of glycine improved subjective sleep quality, reduced next-day fatigue, and improved cognitive performance the following morning in adults with mild sleep complaints.

Can you take both? Yes. Taking magnesium bisglycinate (delivering ~1.7 g glycine) plus an additional 1 to 2 grams of standalone glycine brings your total glycine intake to 3 to 4 grams, matching the study dose while also providing the magnesium benefits. This combination addresses sleep through three distinct mechanisms: magnesium-mediated GABA modulation, magnesium-mediated muscle relaxation, and glycine-mediated thermoregulation. For the comparison with other sleep aids, see best supplements for sleep.

Glycine for sleep: the mechanism and the evidence

Glycine is one of the few compounds where the sleep mechanism is both well-characterized and distinct from other sleep supplements. Unlike melatonin (circadian signaling) or magnesium (GABA modulation), glycine promotes sleep through core body temperature reduction. The Kawai 2015 study demonstrated that oral glycine (3 g before bed) increased blood flow to peripheral extremities (hands and feet), facilitating heat dissipation from the body core. This drop in core temperature is a physiological prerequisite for sleep onset, the same mechanism that makes a cool bedroom help you fall asleep.

Glycine also acts as an inhibitory neurotransmitter at glycine receptors in the brainstem, contributing a direct calming effect that complements the thermoregulatory pathway. The Inagawa 2006 study found that 3 grams of glycine before bed improved subjective sleep quality and reduced next-day fatigue in volunteers with mild sleep complaints. The Bannai 2012 study confirmed these findings using polysomnography, demonstrating that glycine shortened sleep onset latency and increased time spent in slow-wave (deep) sleep without altering total sleep duration.

The practical implication: glycine works on the first night at the first dose. There is no loading period, no accumulation required, no 4-to-8-week wait. For acute sleep needs (jet lag, one-off insomnia, pre-event anxiety), 3 grams of glycine taken 30 to 60 minutes before bed is one of the fastest-acting evidence-based options available. For ongoing use, it can be taken nightly without documented tolerance or dependency development.

The glycine-magnesium glycinate connection

Here is why magnesium glycinate is the preferred sleep form of magnesium: every capsule delivers both magnesium (GABA modulation + muscle relaxation) and glycine (temperature regulation + inhibitory neurotransmission). A 400 mg elemental magnesium bisglycinate dose contains approximately 2,800 mg of the compound, of which roughly 2,400 mg is glycine. This approaches the 3,000 mg glycine dose used in the sleep studies, meaning magnesium glycinate may deliver a meaningful glycine dose alongside the magnesium benefit — effectively a two-in-one sleep supplement.

If you are already taking magnesium glycinate at 400 mg elemental before bed, you may not need a separate glycine supplement. If you want the full 3,000 mg glycine dose studied in the Inagawa and Bannai trials, you can top up with 500 to 1,000 mg of standalone glycine powder (inexpensive and nearly tasteless dissolved in water). See magnesium glycinate benefits and magnesium glycinate sleep research.

Who should be cautious with glycine

People taking clozapine. Glycine can reduce the effectiveness of clozapine, an antipsychotic medication. If you take clozapine, do not supplement glycine without your psychiatrist's guidance.

People with kidney or liver disease. Because glycine is an amino acid processed by the liver and kidneys, those with significant organ impairment should consult their doctor before taking supplemental doses.

People taking other medications. While glycine has few documented interactions, it can have additive effects with sedatives because of its calming action on the nervous system. If you take sleep medication or sedatives, be aware of this.

Pregnant or breastfeeding women. Glycine is naturally present in the diet and body, but concentrated supplemental doses have not been well studied in pregnancy. Consult your provider before regular supplementation.

Glycine is generally very safe and well tolerated, with mild GI upset (nausea, soft stools) being the most common effect at higher doses. It is considered one of the gentler amino acid supplements.

Frequently Asked Questions

What the evidence actually shows

This is one of those supplements where the evidence is actually ahead of the hype. While most people have never considered it as a standalone supplement, the research base, particularly for sleep — is stronger than many more popular options. Three grams before bed. Consistent nightly use. Multiple controlled trials showing real effects on sleep quality, latency, and next-day function.

Beyond sleep, glycine's roles in collagen synthesis, inflammation control, and metabolic health make it genuinely multi-functional, not in the vague "supports general wellness" way, but through specific, documented mechanisms in specific physiological systems. Anyone taking magnesium glycinate is already getting a meaningful glycine dose as part of the deal. If you want the full 3g sleep dose, adding standalone glycine powder or increasing your magnesium glycinate intake is a straightforward next step.

Why we wrote this article: YourHealthier sells magnesium glycinate, which contains glycine as part of its molecular structure. We also sell standalone supplements in related categories. All health claims in this article are sourced from published, peer-reviewed research. See our Editorial Policy.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This article is for informational purposes only and is not a substitute for professional medical advice. Consult your healthcare provider before starting any new supplement, especially if you take medications or have a medical condition.

Related Reading

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• Magnesium Glycinate for Sleep
• Magnesium Glycinate Dosage
• Magnesium Glycinate Side Effects
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References

1. Soto-Diaz, K., Juda, M., Giannakopoulos, P., & Bhatt, D. (2024). The effect of glycine administration on the characteristics of physiological systems in human adults: A systematic review. GeroScience, 46, 3145–3166. PMC
2. Kawai, N., Sakai, N., Okuro, M., et al. (2015). The sleep-promoting and hypothermic effects of glycine are mediated by NMDA receptors in the suprachiasmatic nucleus. Neuropsychopharmacology, 40(6), 1405–1416. PubMed
3. Meléndez-Hevia, E., De Paz-Lugo, P., Cornish-Bowden, A., & Cárdenas, M. L. (2009). A weak link in metabolism: the metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis. Journal of Biosciences, 34(6), 853–872. PubMed
4. Aguayo-Cerón, K. A., Sánchez-Muñoz, F., Gutierrez-Rojas, R. A., et al. (2023). Glycine: The Smallest Anti-Inflammatory Micronutrient. International Journal of Molecular Sciences, 24(14), 11236. PubMed
5. Ramos-Jiménez, A., Hernández-Torres, R. P., Hernández-Ontiveros, D. A., et al. (2024). An Update of the Promise of Glycine Supplementation for Enhancing Physical Performance and Recovery. Sports, 12(10), 265. PMC
6. Yamadera, W., Inagawa, K., Chiba, S., Bannai, M., Takahashi, M., & Nakayama, K. (2007). Glycine ingestion improves subjective sleep quality in human volunteers, correlating with polysomnographic changes. Sleep and Biological Rhythms, 5(2), 126–131.
7. Bannai, M., & Kawai, N. (2012). New therapeutic strategy for amino acid medicine: glycine improves the quality of sleep. Journal of Pharmacological Sciences, 118(2), 145–148. PubMed

Disclosure: YourHealthier manufactures and sells magnesium glycinate discussed in this article. All health claims are based on published peer-reviewed research cited above. We earn revenue from product sales linked in this article.