Ashwagandha Root: Benefits, Root vs. Leaf, Extract vs. Powder & Safety (2026)
Ashwagandha root is the dried root of Withania somnifera, the part of the plant used in Ayurveda and in almost every human trial. Root extracts at 250–600 mg a day lowered stress scores and cortisol in randomized trials, and a 2022 meta-analysis found large effects on stress and anxiety, though with low certainty. Since April 2026, India allows only the root in supplements and foods because the leaves carry more withaferin A. When you buy, look for the words "root" or "root extract" on the label, a stated withanolide percentage, and third-party testing.
Root and leaf are different: the clinical research behind ashwagandha's stress and sleep benefits used the root, while the leaf carries more withaferin A. A 2022 meta-analysis found large reductions in stress and anxiety at 250–600 mg a day of root extract. Since April 2026, India permits only root in supplements. When buying, look for "root extract," a stated withanolide percentage, and third-party testing.
Most ashwagandha labels just say "ashwagandha." That used to be good enough. It isn't anymore.
In April 2026, India, which grows most of the world's supply, banned ashwagandha leaves from supplements and food and required labels to state which part of the plant is inside. Several European countries have restricted the herb altogether. Meanwhile, the clinical research that made ashwagandha popular was done almost entirely on the root. So if you're shopping for ashwagandha root, or wondering whether the bottle you already own is root, this guide covers what you need to know: what the root is, how it differs from the leaf, root powder versus root extract, what the trials found and at what dose, and who should not take it.
Ashwagandha root at a glance
Ashwagandha root is the dried root of Withania somnifera, the plant part used in Ayurveda and in nearly every human clinical trial of the herb. The table below covers how it differs from the leaf and what to check on a label.
| Question | Short answer |
|---|---|
| Botanical name | Withania somnifera (L.) Dunal, nightshade family (Solanaceae) |
| Other names | Indian ginseng, winter cherry, ashwagandha herb |
| Part used traditionally | Root |
| Main active compounds | Withanolides (steroidal lactones), plus alkaloids and saponins |
| Doses in most human trials | 250–600 mg a day of root extract, for 8–12 weeks |
| Best-supported uses | Stress, anxiety, sleep quality; smaller evidence for strength and male fertility |
| Key safety flags | Pregnancy, thyroid conditions, rare liver injury, sedative and thyroid medication interactions |
| Regulatory status (Sept 2026) | Legal as a supplement in the U.S.; root-only rule in India; banned or restricted in several EU countries |
What is ashwagandha root?
The ashwagandha plant (Withania somnifera) is a small woody shrub, usually two to four feet tall, with oval green leaves, pale yellow-green flowers and orange-red berries wrapped in a papery husk. It grows wild across India, the Middle East and parts of Africa, and it's farmed mainly in the Indian states of Madhya Pradesh and Rajasthan. The name comes from Sanskrit and is usually translated as "smell of the horse," a nod both to the fresh root's odor and to the old belief that it gave the strength of a horse.
The root is the part Ayurvedic practitioners have used for centuries. Harvested plants are pulled after the berries ripen, and the long, pale, carrot-shaped taproots are washed, cut and dried. At that point you can do one of two things with them: grind the dried root into a fine beige powder, or run it through an extraction process that concentrates the active compounds. Everything on the supplement shelf, from loose organic ashwagandha powder to branded capsules, comes from one of those two paths.
The compounds researchers care about most are withanolides, a family of steroidal lactones found throughout the plant. The mix differs by plant part. Withanolide A is made in the root itself (Sangwan et al., 2008), while the leaves carry much higher amounts of withaferin A, a more reactive compound that is useful in cancer cell research but raises different safety questions for daily use. That difference is the heart of the current root-versus-leaf debate.
The ashwagandha plant: root, leaf and berry compared
| Plant part | Traditional use | Human clinical data | 2026 status in India |
|---|---|---|---|
| Root | Core Ayurvedic ingredient for centuries | Most published trials | Permitted |
| Leaf | Occasional topical use, not a classical oral ingredient | A few trials of root-plus-leaf extracts | Prohibited in foods and supplements |
| Berry and seed | Used to curdle milk in some regions | Virtually none as a supplement | Not an approved supplement ingredient |
Why would anyone put leaves in a product at all? Mostly cost and marketing. Leaves regrow and are cheaper than roots, and because they are rich in withaferin A, adding leaf extract can push a product's total withanolide percentage up on paper. A capsule claiming "10% withanolides" may contain less root than one claiming 5% if the higher number comes from leaf. Industry sources and Indian regulators have both described leaf being blended in while the label simply said "ashwagandha" (NutraIngredients, April 2026).
Ashwagandha root vs. leaf: why the part now matters
On April 15, 2026, India's Ministry of Ayush ordered that only ashwagandha roots may be used in Ayush medicines. The next day, the Food Safety and Standards Authority of India (FSSAI) extended the rule to health supplements, nutraceuticals and other food products, prohibiting leaves "in crude or extract or any other form" and requiring the plant part to be declared on labels (FSSAI advisory, April 2026). The ministry pointed to a 2024 government safety dossier that recommended the root and flagged the higher withaferin A content of leaves. A 2021 advisory had already told manufacturers to avoid leaves, and it was widely ignored.
The rule has not settled the argument. Makers of root-plus-leaf extracts say their products have their own safety and efficacy trials, and in May 2026 the Karnataka High Court granted petitioners an interim stay of both the Ayush directive and the FSSAI advisory while the case is heard (New Hope Network, September 2026). So the legal picture inside India is still moving.
Europe is going further. Denmark has banned ashwagandha in food supplements since 2023. France has restricted it, Belgium treats it as a medicinal substance, Poland caps daily intake at 3 grams of powdered root or 10 mg of withanolides, and Hungary limits it to 250 mg of dried root (Nutraceuticals World; New Hope Network). In 2024, the heads of EU national food safety agencies asked for the herb to be prioritized for an EU-level review. The Dutch health ministry announced plans for a ban in early 2026 (Vitafoods Insights), and Finland and Sweden are weighing limits. Critics of the Danish assessment point out that it lumped root and leaf data together.

In the U.S., nothing has changed. Ashwagandha root and leaf are both legal in dietary supplements, and labels are not required to say which part is inside. That leaves the checking to you, which is what the rest of this guide is for.
How to tell if your product is root-only
- Read the Supplement Facts line itself. "Ashwagandha (Withania somnifera) root extract" or "root powder" is what you want to see. "Ashwagandha extract" or "aerial parts" with no plant part named is a question mark.
- Know the branded ingredients. KSM-66 is marketed as root-only. Sensoril and Shoden are extracts made from root and leaf. Both of those have their own clinical studies, but they are not root-only.
- Be wary of unusually high withanolide claims. Root extracts are commonly standardized to around 1.5–5% withanolides. Much higher numbers can come from leaf content or from lab methods that inflate results.
- Ask for a certificate of analysis. A good brand can tell you the plant part, the withanolide percentage and the heavy metal results for your lot.
Ashwagandha root benefits: what the trials found
Ashwagandha has a large and growing body of human research, but it is uneven, and most of the ashwagandha root benefits you read about online rest on a few dozen small trials. Many trials are small, run over 8 to 12 weeks, and funded by the companies that make the extract. With that caveat noted, the root studies show the following.
Stress and cortisol
This is the strongest area. In a 60-day trial, 64 adults with chronic stress took 300 mg of a full-spectrum root extract twice a day or a placebo. The ashwagandha group scored lower on every stress scale used and had a meaningful drop in serum cortisol, about 28% from baseline, with side effects similar to placebo (Chandrasekhar et al., 2012).
A 2019 trial tested two doses of root extract in 60 healthy adults for eight weeks. Both 250 mg and 600 mg a day lowered perceived stress and cortisol compared with placebo, with the larger dose doing more, and sleep quality improved as well (Salve et al., 2019). That lower-dose result is useful if you are sensitive to supplements or want to start small.
Pooling the data, a 2022 meta-analysis of 12 randomized trials with 1,002 participants found ashwagandha reduced stress and anxiety compared with placebo, with standardized effect sizes of −1.75 for stress and −1.55 for anxiety. The dose-response analysis favored 300–600 mg a day for stress. The authors also rated the certainty of the evidence as low, largely because the trials varied so much (Akhgarjand et al., 2022).

For a closer look at the hormone side, see our guide to ashwagandha, cortisol and stress relief.
Sleep
In a 10-week trial of adults with insomnia and anxiety, 300 mg of root extract twice a day shortened the time it took to fall asleep and raised sleep efficiency from about 76% to 83%, a bigger gain than placebo (Langade et al., 2019). A 2021 meta-analysis of five trials and 400 people found a small but significant overall benefit for sleep. The effect was larger in people who actually had insomnia, at 600 mg a day or more, and after at least eight weeks (Cheah et al., 2021).
Ashwagandha is not a sleeping pill. Most people who notice a sleep benefit describe it as falling asleep more easily over several weeks, not as knocking out on night one. We cover timing in detail in ashwagandha for sleep.
Strength and training recovery
In an eight-week study, 57 men aged 18 to 50 who were new to resistance training took 300 mg of root extract twice a day or a placebo. The ashwagandha group gained more strength on the bench press (46 kg vs. 26 kg) and the leg extension, and added more muscle size at the arms and chest (Wankhede et al., 2015). It is one trial with a small sample, so treat it as promising rather than settled.
Male fertility and testosterone
In 46 men with low sperm counts, 675 mg a day of root extract for 90 days raised sperm count by 167%, semen volume by 53% and sperm motility by 57%, with much smaller changes on placebo (Ambiye et al., 2013). Hormone levels also improved. This is a pilot study in men with a specific problem, so it does not mean ashwagandha will raise testosterone in healthy men. Our ashwagandha and testosterone article covers the wider evidence.
Thyroid: a benefit and a warning
In 50 adults with subclinical hypothyroidism, 600 mg a day of root extract for eight weeks lowered TSH and raised T3 and T4 compared with placebo (Sharma et al., 2018). That sounds like good news, and for some people it may be. It also means ashwagandha can shift thyroid hormones, which is a problem if you have an overactive thyroid or take levothyroxine, because your dose may no longer be right. Anyone with a thyroid condition should check with their doctor and get labs rechecked if they start it.
What the evidence does not support
You will see ashwagandha root marketed for weight loss, memory, blood sugar, immunity, hair growth and cancer prevention. Some of these have small or early studies, many come from animal or cell work, and none has the kind of repeated human evidence that stress and sleep do. If a brand leads with those claims, weigh them accordingly. Our broader ashwagandha benefits guide sorts the claims by evidence level.
Ashwagandha root extract vs. ashwagandha root powder
This is the practical choice most buyers face, and it changes how much you need to take.
Ashwagandha root powder is the whole dried root, ground. Nothing is concentrated or removed. It's the traditional form: in Ayurveda it's often stirred into warm milk with honey or ghee at night. Powder is inexpensive, easy to find as organic ashwagandha powder, and useful if you want to cook with it or make a root tea. Its withanolide content is low and unpredictable, typically well under 1% and varying with the soil, harvest and batch.
Ashwagandha root extract is made by soaking the root in water, milk, alcohol or a mix, then drying the liquid down to a concentrated powder. Good extracts are standardized to a stated withanolide percentage, often somewhere between 1.5% and 5%. That standardization is why nearly every clinical trial used an extract: researchers need to know how much active material each dose delivers.
| Root powder | Root extract | |
|---|---|---|
| What it is | Whole ground root | Concentrated, usually standardized |
| Withanolide content | Low, variable | Stated on label (often 1.5–5%) |
| Typical serving on labels | Several grams | 250–600 mg |
| Used in clinical trials? | Rarely | Almost always |
| Taste | Bitter, earthy; hard to mask | Usually in capsules, so taste is not an issue |
| Cost per serving | Lower | Higher |
| Best for | Traditional use, teas, milk drinks, cooking | Matching the doses studied in trials |
One common mistake is swapping 600 mg of root powder for 600 mg of extract. They are not equivalent. Because trials almost always used extracts, there is little data to tell you how much plain powder matches a given extract dose. If research-backed dosing is your goal, the extract is the simpler route. If you like the ritual of the powder, our ashwagandha powder guide and ashwagandha tea guide cover preparation.
Can you trust the withanolide number on the label?
Not always. There is still no widely accepted, validated lab method for anything other than root preparations, and industry experts told New Hope Network in September 2026 that commercial withanolide content has been found to deviate from label claims by anywhere from 2-fold to 35-fold. One consultant said extracts sold as 5% withanolides frequently test at less than a tenth of that (New Hope Network, 2026). A standardized number is still better than no number, but a certificate of analysis from an independent lab, tied to your lot, is what actually tells you what is in the capsule.
Does organic ashwagandha matter?
USDA Organic or India Organic certification tells you how the plant was grown and processed. It doesn't tell you the plant part, the withanolide content or the heavy metal level. Ashwagandha is a root crop, and roots pick up lead, cadmium and arsenic from soil, so independent heavy metal testing is worth more than an organic seal alone. The ideal label has both, plus the word "root." "Pure ashwagandha" on the front of a bottle is a marketing phrase and tells you nothing about which part of the plant is inside.
What about KSM-66 and other branded root extracts?
KSM-66 is a branded full-spectrum root extract standardized to at least 5% withanolides, and it is the extract used in many of the trials above. Whether it is worth the higher price compared with a generic root extract depends on your goal and budget, and we compare them head to head in KSM-66 vs. regular ashwagandha. If you are new to the name, start with what KSM-66 is.

How to take ashwagandha root
Form. Ashwagandha root capsules or tablets make it easy to match the doses in the research. Powder works in warm milk, smoothies or an ashwagandha root tea, but the dose is harder to pin down. Gummies are another option: our Goli Ashwagandha review shows the dose and sugar trade-offs, and our ashwagandha gummies guide compares the format more broadly.
Dose. For root extract, the trials above used 250 to 675 mg a day, most often 600 mg split into two 300 mg doses. Starting at 250–300 mg a day for a week or two is a sensible way to check how you react. For more detail by goal, see our ashwagandha dosage guide.
Timing. Either time of day can work. People taking it mainly for sleep often take it in the evening; people who feel drowsy on it should avoid mornings before driving. Taking it with food reduces stomach upset. Our article on when to take ashwagandha goes through the options.
How long before it works. Most trials measured results at 8 to 12 weeks. Some people notice calmer days within two weeks, but a fair trial is about two months at a steady dose. More on that in how long ashwagandha takes to work.
How long to stay on it. This is where the evidence is thin. Most studies lasted three months or less, so long-term safety data is limited. Many clinicians suggest reassessing after three months and taking a break, especially given the liver and thyroid questions below.
Ashwagandha root side effects
In trials, ashwagandha root extract is usually well tolerated. An eight-week safety study in 80 healthy adults taking 300 mg twice a day found no meaningful changes in vital signs, blood counts, liver and kidney markers, or thyroid hormones compared with placebo, and no adverse events were reported (Verma et al., 2021). Outside of trials, the most common complaints are:
- Stomach upset, nausea or loose stools, especially on an empty stomach
- Drowsiness or feeling flat
- Headache
- Vivid dreams, in some people
Liver injury is rare but real. A case series from Iceland and the U.S. Drug-Induced Liver Injury Network described patients who developed jaundice, itching and nausea 2 to 12 weeks after starting ashwagandha. The injury was cholestatic, none progressed to liver failure, and liver tests returned to normal within one to five months in the patients who were followed up (Björnsson et al., 2020). If you notice dark urine, yellowing of the skin or eyes, or itching without a rash, stop and see a doctor. Our ashwagandha liver safety page covers the case reports in more depth.
For the full list, including less common effects, see ashwagandha side effects.
Who should avoid ashwagandha root
- Pregnant or breastfeeding people. Traditional texts describe it as able to induce miscarriage at high doses, and there is no safety data in pregnancy. See ashwagandha and pregnancy.
- People with hyperthyroidism, or anyone on thyroid medication without their doctor's input.
- People with autoimmune conditions such as lupus, rheumatoid arthritis or multiple sclerosis, because ashwagandha may stimulate immune activity.
- Anyone with liver disease or a history of drug-induced liver injury.
- People scheduled for surgery. Stop about two weeks before, since it may add to the effect of anesthesia and sedatives.
- People with hormone-sensitive prostate cancer, given its possible effect on testosterone.
Possible drug interactions include sedatives and benzodiazepines, thyroid hormone, immunosuppressants, and medications for blood sugar and blood pressure. The full list is in our ashwagandha drug interactions guide.
Ashwagandha root with maca root or valerian root
Ashwagandha is often sold in blends with other roots, and two pairings come up constantly in searches: maca root and valerian root.
Maca root and ashwagandha. Maca (Lepidium meyenii) is a Peruvian root vegetable usually marketed for energy and libido. A systematic review of four randomized trials found limited evidence that maca improves sexual function, and the authors flagged small sample sizes and weak methods (Shin et al., 2010). There are no published trials testing maca and ashwagandha together, so any "synergy" claim on a label is a hypothesis. The pairing is generally considered low risk for healthy adults, and people often take ashwagandha for stress and maca for energy in the same routine.
Valerian root with ashwagandha. Valerian is a traditional European sleep herb. A meta-analysis of 16 studies with 1,093 people found valerian might improve sleep quality, but most studies had significant methodological problems and there was evidence of publication bias (Bent et al., 2006). Combining two calming herbs can add up, so start with low doses of each, take them at night, and avoid pairing them with alcohol, benzodiazepines or prescription sleep medication unless your doctor agrees.
Other common pairings include magnesium, which we cover in ashwagandha and magnesium glycinate together, and rhodiola, compared in ashwagandha vs. rhodiola.
Can you grow an ashwagandha plant and use your own root?
You can grow ashwagandha at home. Seeds and starter plants are sold online and at some nurseries, and the plant does well in full sun, sandy well-drained soil and warm weather. In cooler climates it is usually grown as an annual. Commercial growers in India typically harvest the roots five to six months after sowing, once the berries ripen and the leaves start to dry.
Growing it's a fun project, and the dried root can go into tea. As a supplement, though, homegrown root has two drawbacks. You have no idea how much withanolide it contains, and it can pick up heavy metals from garden soil. Also keep the berries and leaves away from children and pets: like other members of the nightshade family, parts of the plant should not be eaten raw.
How to choose an ashwagandha root supplement
Put these six checks together and you will filter out most weak products in a couple of minutes:
- The label names the root. "Root" or "root extract" in the Supplement Facts panel, not just "ashwagandha."
- A withanolide percentage is stated, and it is in a realistic range for root.
- The dose matches the research. Roughly 250–600 mg of extract per day, not a sprinkle inside a proprietary blend.
- Third-party testing is available for identity, potency and heavy metals, either as a seal or a lot-specific certificate of analysis.
- The formula fits your goal. Ashwagandha on its own is easiest to judge. Combination products can be useful, but more ingredients means more variables.
- The claims are modest. "Supports a healthy stress response" is normal supplement language. Promises to cure anxiety, fix your thyroid or melt fat are not.
If you want to compare specific products, our ashwagandha brand reviews look at popular options.
Where our product fits. YourHealthier Ashwagandha Plus uses 600 mg of KSM-66 root-only extract, standardized to 5% withanolides, which is the dose and extract type used in several of the trials above. It also contains maca, Panax ginseng, shatavari, L-arginine and vitamins D3, B6 and B12, so it's a combination formula. If you want ashwagandha root on its own, a single-ingredient root extract is the cleaner choice. If you like the idea of pairing it with other adaptogens, the combination may suit you. The safety cautions in this guide apply to it the same as to any ashwagandha product.
Final take on ashwagandha root
Among the parts of Withania somnifera, the root carries the longest history of use and nearly all of the clinical evidence. The leaves, berries and stems of the ashwagandha plant have a much thinner record, and in 2026 the leaf became the focus of bans and court cases. At 250 to 600 mg a day of a standardized root extract, it has reasonably consistent data for lowering stress and cortisol, easing anxiety and improving sleep over 8 to 12 weeks, with early data on strength and male fertility. The certainty of that evidence is moderate at best, and a small number of people develop liver problems or thyroid shifts.
The 2026 root-only rule in India is a useful signal even if you shop in the U.S. Choose products that name the root on the label, state their withanolide content, and can show independent testing. Skip it if you are pregnant, have a thyroid or autoimmune condition, or have liver trouble, unless your doctor says otherwise.
Ashwagandha root FAQ
What is ashwagandha root used for?
Ashwagandha root is used mostly for stress, anxiety and sleep — randomized trials of root extract at 250–600 mg a day have shown lower stress scores and cortisol, less anxiety and better sleep quality over about 8 to 12 weeks. Smaller studies have looked at strength training and male fertility.
Is ashwagandha root better than the leaf?
The root has the traditional track record and most of the clinical data. Leaves contain more withaferin A, and India banned leaves in foods and supplements in April 2026 over safety concerns. Some root-plus-leaf extracts have their own trials, but root-only is the more conservative choice.
Is ashwagandha root powder as good as extract?
No — they are different products: root powder is the whole ground root with low, variable withanolide content, while extracts are concentrated. Extracts are concentrated and standardized, and they are what almost every clinical trial used. For trial-matched dosing, choose a standardized root extract.
How much ashwagandha root should I take?
Studies used 250–675 mg a day of root extract, most often 600 mg split into two doses. Starting at 250–300 mg a day is reasonable. Plain root powder doses are larger and less standardized.
What are the most common ashwagandha root side effects?
Most people tolerate ashwagandha root well, but common side effects include stomach upset, drowsiness and headache. Rare cases of cholestatic liver injury have been reported, and it can change thyroid hormone levels.
Who should not take ashwagandha root?
People who are pregnant or breastfeeding, have hyperthyroidism or take thyroid medication, have autoimmune or liver disease, have hormone-sensitive prostate cancer, or have surgery coming up should avoid it or talk to a doctor first.
Is organic ashwagandha root better?
Not necessarily — organic certification covers farming practices, not quality: it doesn't guarantee root-only content, withanolide levels or low heavy metals. Look for "root" on the label and third-party heavy metal testing in addition to any organic seal.
Is ashwagandha root legal in the U.S. and Europe?
It is legal as a dietary supplement in the U.S. Denmark bans it in food supplements, several other EU countries restrict it, and an EU-level review has been requested. Rules are changing, so check local regulations if you live outside the U.S.
Can I take ashwagandha root with maca root or valerian root?
Most healthy adults can, but neither combination has been tested in trials. Ashwagandha plus valerian can add up to more drowsiness, so start low and take it at night. Check with a doctor if you take sedatives or sleep medication.
References
- Chandrasekhar K, Kapoor J, Anishetty S. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 2012. PMID: 23439798
- Salve J, Pate S, Debnath K, Langade D. Adaptogenic and anxiolytic effects of ashwagandha root extract in healthy adults: a double-blind, randomized, placebo-controlled clinical study. Cureus. 2019. PMID: 32021735
- Akhgarjand C, Asoudeh F, Bagheri A, et al. Does ashwagandha supplementation have a beneficial effect on the management of anxiety and stress? A systematic review and meta-analysis of randomized controlled trials. Phytother Res. 2022. PMID: 36017529
- Langade D, Kanchi S, Salve J, et al. Efficacy and safety of ashwagandha (Withania somnifera) root extract in insomnia and anxiety: a double-blind, randomized, placebo-controlled study. Cureus. 2019. PMID: 31728244
- Cheah KL, Norhayati MN, Husniati Yaacob L, Abdul Rahman R. Effect of ashwagandha (Withania somnifera) extract on sleep: a systematic review and meta-analysis. PLoS One. 2021. PMID: 34559859
- Wankhede S, Langade D, Joshi K, et al. Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial. J Int Soc Sports Nutr. 2015. PMID: 26609282
- Ambiye VR, Langade D, Dongre S, et al. Clinical evaluation of the spermatogenic activity of the root extract of ashwagandha (Withania somnifera) in oligospermic males: a pilot study. Evid Based Complement Alternat Med. 2013. PMID: 24371462
- Sharma AK, Basu I, Singh S. Efficacy and safety of ashwagandha root extract in subclinical hypothyroid patients: a double-blind, randomized placebo-controlled trial. J Altern Complement Med. 2018. PMID: 28829155
- Verma N, Gupta SK, Tiwari S, et al. Safety of ashwagandha root extract: a randomized, placebo-controlled study in healthy volunteers. Complement Ther Med. 2021. PMID: 33338583
- Lopresti AL, Smith SJ, Malvi H, Kodgule R. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: a randomized, double-blind, placebo-controlled study. Medicine (Baltimore). 2019. PMID: 31517876
- Sangwan RS, Das Chaurasiya N, Lal P, et al. Withanolide A is inherently de novo biosynthesized in roots of the medicinal plant ashwagandha (Withania somnifera). Physiol Plant. 2008. PMID: 18312497
- Björnsson HK, Björnsson ES, Avula B, et al. Ashwagandha-induced liver injury: a case series from Iceland and the US Drug-Induced Liver Injury Network. Liver Int. 2020. PMID: 31991029
- Shin BC, Lee MS, Yang EJ, et al. Maca (L. meyenii) for improving sexual function: a systematic review. BMC Complement Altern Med. 2010. PMID: 20691074
- Bent S, Padula A, Moore D, et al. Valerian for sleep: a systematic review and meta-analysis. Am J Med. 2006. PMID: 17145239
- Food Safety and Standards Authority of India. Advisory on non-use of ashwagandha leaves in crude or extract or any other form in food products. April 16, 2026. fssai.gov.in
- NutraIngredients. India bans ashwagandha leaf use in any form, industry reacts. April 28, 2026. nutraingredients.com
- New Hope Network. Ashwagandha's market faces crisis as regulators clash over leaf versus root standards. September 2026. newhope.com
- Nutraceuticals World. Ashwagandha safety questioned in Europe and India. nutraceuticalsworld.com
- Vitafoods Insights. Use of ashwagandha leaves is banned in India. Should the EU follow suit? vitafoodsinsights.com
This article is for general information and is not medical advice. Talk with a doctor or pharmacist before starting ashwagandha, especially if you are pregnant, breastfeeding, have a thyroid, liver or autoimmune condition, or take prescription medication. YourHealthier sells an ashwagandha product mentioned above. This page has no affiliate links, and we did not receive free product from any brand mentioned. Regulatory details were checked on September 27, 2026 and may change.
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Sources verified: All PubMed citations and external references in this article were last verified on September 28, 2026.
Disclosure: YourHealthier manufactures and sells the supplements discussed in this article. All health claims are based on published peer-reviewed research cited above. We earn revenue from product sales linked in this article.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before starting any supplement regimen.
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