Omre NMN + Resveratrol Review 2026: 500 mg Combo Formula, BioPerine, and What the Evidence Says

The Formula: What Is in the Capsule

Each two-capsule serving contains 500 mg of NMN (stated 99% purity, using Uthever NMN powder), 500 mg of micronized trans-resveratrol (98% purity), and 5 mg of BioPerine black pepper extract. The capsules are vegetarian, vegan, gluten-free, soy-free, and dairy-free.

Product page data accessed October 17, 2026. The label lists three active ingredients in a 1:1 NMN-to-resveratrol ratio, which is unusual in this market. Most NMN supplements are NMN-only. The handful that add resveratrol typically use less of it: Wonderfeel Youngr includes 100 mg of resveratrol beside 900 mg of NMN, and GenuinePurity includes none.

The NMN raw material is Uthever, manufactured by Effepharm and one of the most widely used branded NMN ingredients in the supplement industry. Uthever appears in products from multiple brands. Using a recognized ingredient supplier is a reasonable quality signal, though it means the NMN powder itself is not exclusive to Omre.

"Micronized" resveratrol refers to grinding the powder into smaller particles, which in theory increases surface area and dissolution. Micronization is a standard pharmaceutical technique, but no published study has compared micronized trans-resveratrol head-to-head with unmicronized resveratrol in people at matched doses.

Omre also sells berberine, TMG + B-Complex, urolithin A, spermidine, and a glycine-NAC blend under the same brand. The NMN + Resveratrol capsule is the flagship. That context matters because a brand with a wider line is less likely to disappear overnight than a one-product operation, which is a small but real consideration when buying supplements you plan to take for months.

One detail worth checking: the label says 99% NMN purity, but earlier third-party scoring sites listed 98%. The difference is one percentage point and about 5 mg of NMN per serving, which is trivial in practice. What matters more is whether the certificate for your lot confirms the β form of NMN and reports contaminant levels. We cover what to look for in our COA checklist.

NMN and Resveratrol Together: What the Mouse Study Found

One mouse study tested NMN combined with resveratrol and found that the combination raised NAD+ in certain tissues, including heart and skeletal muscle, more than NMN alone. That study was in mice, not humans, and no clinical trial has replicated it.

The study most often cited to support the combination gave mice 500 mg/kg of NMN followed by 50 mg/kg of resveratrol and measured NAD+ across tissues. The NMN-plus-resveratrol group showed higher NAD+ in heart and skeletal muscle than NMN alone (Bai et al., 2022). The result is interesting and also limited: mouse doses do not translate directly to human doses, and the study did not measure health outcomes.

The theoretical basis is straightforward. NMN converts to NAD+ inside cells. Resveratrol activates SIRT1, a protein that consumes NAD+ to regulate gene expression, DNA repair, and metabolism. The logic is that supplying both the fuel (NAD+) and an activator of the enzyme that burns it could produce a stronger effect than either alone. A 2022 review of sirtuin-activating nutraceuticals described this rationale but noted that human combination data is still missing (DiNicolantonio et al., 2022).

Until a human trial gives matched groups NMN alone and NMN plus resveratrol and measures NAD+ or a clinical endpoint, the combination remains a hypothesis supported by animal data. That does not make it wrong. It means the buyer is paying for two ingredients whose interaction has not been confirmed in people. Our NMN and resveratrol guide covers the combination question in detail.

The BioPerine Claim: What Piperine Does to Resveratrol

In mice, piperine increased resveratrol bioavailability by 229%. A small human pilot study found a trend toward higher resveratrol blood levels with 5 mg of piperine but the result was not statistically significant. The BioPerine addition has a plausible mechanism; it does not have strong human proof at the 5 mg dose in Omre's formula.

Resveratrol is rapidly metabolized after swallowing. Most of it is converted to glucuronide and sulfate conjugates in the gut and liver before reaching the bloodstream, which is why its oral bioavailability is low despite high absorption. Piperine inhibits glucuronidation, the main clearance pathway, which in theory slows elimination and raises circulating levels.

A 2011 mouse study gave 100 mg/kg of resveratrol with or without 10 mg/kg of piperine. The piperine group showed a 229% increase in resveratrol exposure (AUC) and a 1,544% increase in peak serum concentration (Johnson et al., 2011). That result was dramatic enough to prompt a human follow-up.

The human study was a randomized, double-blind pilot in healthy volunteers. Subjects received resveratrol alone, resveratrol with 5 mg piperine, or resveratrol with 25 mg piperine. At 5 mg, the dose used in Omre's capsule, the AUC for resveratrol was numerically higher (2,083 vs 1,270 ng·h/mL) but the difference was not statistically significant due to high variability. At 25 mg piperine, levels were actually lower than resveratrol alone (Bailey et al., 2021).

In other words, the mouse result was large and the human result was mixed. That is a common pattern in supplement research. BioPerine is a reasonable addition and an honest disclosure. What it is not, based on current evidence, is a proven bioavailability multiplier for resveratrol in people at this dose. Omre's marketing describes it as "absorption support," which is a careful phrasing.

Price and Cost per 500 mg of NMN

Omre's one-time price is $69 for 60 capsules (30 servings), or $2.30 per day. On a per-500-mg-of-NMN basis, the cost is $2.30. That is in the upper third of the NMN market, though the price includes 500 mg of resveratrol and 5 mg of BioPerine that single-ingredient NMN products do not contain.

Product	NMN per serving	Other actives	Cost per 500 mg NMN
Omre NMN + Resveratrol	500 mg	Resveratrol 500 mg, BioPerine 5 mg	about $2.30
YourHealthier NMN (our product)	500 mg	None	about $1.67
ProHealth NMN Pro 500	500 mg	None	about $1.50
Wonderfeel Youngr NMN	900 mg	Resveratrol 100 mg, ergothioneine, vitamin D3, hydroxytyrosol	about $1.63
Nutricost NMN	500 mg	None	about $0.57

The comparison is not entirely fair in either direction. Omre costs more per milligram of NMN than every single-ingredient product on this list. But buying 500 mg of resveratrol separately would add $15 to $30 per month depending on the brand, which narrows the gap for someone who was going to take both. If you only want NMN, there are cheaper options.

Omre also offers bundle pricing and occasional discounts. We priced at the one-time single-bottle rate because that is what a first-time buyer pays. Check the current price on Omre's site before ordering, as supplement prices change frequently. Our own NMN capsule is listed because we sell it and it is a relevant comparison; it is a single-ingredient, non-resveratrol product at a lower price point. Reviews of the other products above are in our ProHealth review, Wonderfeel review, and Nutricost review.

How Omre Markets Itself: The Blog Strategy

Omre publishes dozens of comparison articles on its own blog, each structured around a "four checks" framework where Omre passes all four and competitors pass fewer. These articles rank well in search engines. They are marketing content written and published by Omre, not independent editorial.

Search for almost any NMN brand name plus "review" or "compared" and you will likely find an Omre blog post in the results. We counted more than 20 such articles on omre.co during this review, each following the same template: a comparison table, four quality checks, and a conclusion naming Omre NMN + Resveratrol as the product that "passes all four." Every time.

This is a legitimate and increasingly common content marketing strategy in the supplement industry. It is also worth understanding for what it is. When the company selling the product also writes the review and controls the criteria, the outcome is predetermined. Every check is chosen because the house product passes it. Every competitor is measured against standards the house product was built to meet.

This is not the same as saying the underlying facts are wrong. Omre does publish COAs. Its NMN dose does match trial data. Its purity percentage is stated on the label. But the framing, tone, and editorial judgment in those articles serve the brand's sales goals, and a reader should weigh them the way they would weigh any company's own advertising.

Fortune's 2026 "Best Vegan NMN Supplement" placement is editorially independent of Omre, though many such roundups include affiliate commissions. The distinction between editorial coverage and brand-published content matters when you are deciding what to trust.

We note this not to single out Omre. Our reviews are also not neutral: we sell an NMN product. The difference is that we say so in the comparison table and price our product at its actual retail price. Any review site, including ours, has incentives that a reader should understand before taking its conclusions at face value.

The NMN-vs-NR Framing in Omre's Content

Omre's blog positions NMN as the preferred NAD+ precursor over NR (nicotinamide riboside). The direct comparison data from 2026 shows they raise blood NAD+ by comparable amounts. The precursor choice is less decisive than much NMN marketing suggests.

Several Omre articles include a section on NMN versus NR, typically concluding that NMN is the better choice. A 2026 trial in 65 healthy adults directly compared oral NMN and NR at matched conditions and found comparable NAD+ increases for both, while plain nicotinamide did not raise NAD+ (Christen et al., 2026). A 2021 review noted that NR has a longer clinical track record, with more published human trials, while NMN evidence was growing (Palmer et al., 2021).

For a buyer choosing between an NMN product like Omre and an NR product like Tru Niagen, the precursor itself is probably not the deciding factor. Price, dose, and what else is in the capsule matter more. Our NMN vs NR comparison covers this question without a stake in the answer, since we sell NMN and not NR.

Documentation and Testing

Omre describes a dual-stage testing process: raw ingredients are tested before encapsulation, and finished capsules are retested. The brand publishes COAs and states ISO 17025-accredited third-party testing. We did not review a lot-specific certificate for this article.

Two-stage testing, raw material in and finished product out, is a meaningful quality step that many supplement brands skip. If Omre does this consistently, it addresses two different failure points: the ingredient could be mislabeled coming in, and the encapsulation process could introduce errors or contaminants.

What we could not confirm from public information is which lab performs the testing, what analytes the certificate covers, or whether every batch or only selected batches are tested. Omre's site says COAs are available. Before buying, ask for the certificate matching your lot and check whether it includes a β-NMN identity test, a numeric purity assay, and heavy metal results for lead, arsenic, cadmium, and mercury. Our NMN COA checklist explains what each line means.

Safety of NMN at 500 mg

Multiple human trials have tested NMN at 500 mg per day or higher. The highest published dose is 1,250 mg daily for four weeks, with no significant adverse events. A 2026 meta-analysis found oral NMN well tolerated overall. Resveratrol has been tested in humans at doses up to 5,000 mg daily. NMN is lawful as a US dietary supplement following the FDA's September 2025 reversal.

Omre's 500 mg NMN dose falls within a well-tested range. Single oral doses of 100 to 500 mg were safe in the first human NMN trial (Irie et al., 2020). A four-week study at 1,250 mg daily found no serious adverse events (Fukamizu et al., 2022). A 2026 systematic review and meta-analysis of oral NMN trials found it generally well tolerated, while noting that broad metabolic benefits were not yet confirmed (Yang et al., 2026).

Resveratrol has been studied at higher absolute doses. Human studies have used up to 5,000 mg daily. At standard supplement doses of 250 to 500 mg, gastrointestinal discomfort is the most commonly reported side effect. Resveratrol can interact with medications metabolized by cytochrome P450 enzymes, including blood thinners, so check with a doctor if you take prescription drugs.

BioPerine at 5 mg is a small dose with a long safety track record in supplements. However, because piperine inhibits drug-metabolizing enzymes, it can increase the blood levels of certain medications. This is the same mechanism it uses to enhance resveratrol absorption: slowing breakdown. If you take prescription medication, that interaction is worth discussing with your doctor.

On regulatory status, NMN is lawful as a US dietary supplement since the FDA's September 2025 reversal. Our NMN FDA status page covers the timeline. Resveratrol has been sold as a supplement for decades without regulatory challenge.

People who are pregnant, breastfeeding, or taking prescription medication should talk to a doctor before starting any NMN or resveratrol product. This is standard supplement advice, but it carries extra weight here because the formula contains three active ingredients that each have their own interaction profiles. Our NMN side effects guide lists the commonly reported effects from NMN trials.

Does 500 mg of NMN Raise NAD+?

Yes, based on multiple human trials. NMN at 250 to 900 mg daily raised blood NAD+ or its metabolites in studies lasting 6 to 12 weeks. At 500 mg specifically, a 2021 trial in postmenopausal women found improved muscle insulin sensitivity. Higher doses showed dose-dependent NAD+ increases.

Study	Daily NMN dose	Duration	Key result
Irie et al., 2020	100–500 mg (single dose)	Single day	Safe, NMN metabolites detected in blood
Yoshino et al., 2021	250 mg	10 weeks	Muscle insulin sensitivity improved vs placebo
Yi et al., 2023	300, 600, 900 mg	60 days	NAD+ rose with dose; six-minute walk improved in all groups
Liao et al., 2021	300, 600, 1,200 mg	6 weeks	Ventilatory thresholds improved at 600 and 1,200 mg; VO2max unchanged
Christen et al., 2026	oral NMN vs NR	14 days	Both raised blood NAD+ comparably; nicotinamide alone did not

The Christen result is worth noting for Omre specifically. That trial found NMN and NR raised NAD+ by comparable amounts. Omre's marketing often frames NMN as the superior precursor. The direct comparison data says they are similar for this measure.

For context on what NMN does and does not show in humans, a 2026 review of 113 NAD-related studies described clear biological activity but inconclusive evidence for anti-aging or wellness outcomes (Gallagher et al., 2026). Our NMN dosage guide covers how to choose between 250, 500, and higher doses.

Who Omre NMN + Resveratrol Fits

Omre fits someone who specifically wants NMN and resveratrol in a single product and values batch-level documentation. Someone who wants only NMN, or who prioritizes price per milligram, has more efficient options.

The combo buyer. If you were going to buy NMN and resveratrol separately anyway, Omre consolidates them into one bottle and adds BioPerine. The convenience has value, and the total cost may be comparable to two separate products from reputable brands.

The documentation-first buyer. Omre's emphasis on published COAs and dual-stage testing is above the market average. If third-party documentation is your primary purchase criterion, Omre is in the stronger tier alongside ProHealth and Renue by Science.

The NMN-only user. If resveratrol is not part of your plan, you are paying for an ingredient you do not want. A single-ingredient 500 mg NMN capsule from ProHealth, Nutricost, or our own product is simpler and cheaper.

The price-sensitive buyer. At $2.30 per 500 mg of NMN, Omre is among the most expensive options on a pure-NMN basis. Nutricost delivers the same 500 mg for about $0.57 with verified purity. The gap is real.

The skeptic of combo formulas. The NMN-plus-resveratrol thesis has animal support but no human trial. If you want to take only ingredients tested in people in the exact form you are swallowing, a plain NMN capsule matches the trial evidence more closely.

Omre vs Single-Ingredient NMN: A Side-by-Side

The core decision for most buyers is whether the resveratrol addition justifies the price premium over a plain NMN capsule. This table puts the two product types side by side on the points that matter most.

	Omre NMN + Resveratrol	Typical single-ingredient NMN (500 mg)
NMN per serving	500 mg	500 mg
Resveratrol	500 mg micronized trans-resveratrol	None
Additional ingredients	BioPerine 5 mg	None or minimal excipients
Cost per 500 mg NMN	about $2.30	$0.57 to $1.67 depending on brand
Human trial evidence for the exact formula	None (NMN tested alone; resveratrol tested alone; combination tested in mice only)	Multiple trials at 250 to 1,250 mg NMN alone
Capsules per day	2	1 to 2
Drug interaction considerations	NMN, resveratrol (CYP450), and piperine (CYP450) each have potential interactions	NMN interactions only

If you already take resveratrol and plan to continue, Omre saves you a bottle. If you do not take resveratrol and are not convinced by the mouse-level combination evidence, a single-ingredient NMN capsule matches the human trial data more directly and costs less.

Our Verdict on Omre

Omre is a well-documented product selling a hypothesis. The NMN is real, the resveratrol is real, the testing is real. The combination thesis is not.

If you want NMN and resveratrol in one capsule and the convenience justifies the price, Omre delivers. If you want only what has been tested in human trials, a single-ingredient NMN capsule at half the price is the more evidence-aligned choice. We sell one of those, and we say so in the table above.

What We Did Not Cover

We did not request a lot-specific COA, open a bottle, or evaluate Omre's other products (berberine, TMG, urolithin A, spermidine). This review covers only the NMN + Resveratrol capsule using publicly available data through mid-October 2026.

Omre sells several other supplements beyond NMN. We focused on the flagship because it is the product most often compared to single-ingredient NMN supplements. A COA review for a specific lot would add useful detail; we plan to request one for a future update.

YourHealthier sells an NMN product, identified as ours in the price table above. Omre did not sponsor, review, or approve this article before publication.

Omre NMN + Resveratrol FAQ

Common questions about the formula, pricing, and how it compares, based on the product page and the evidence above.

How much NMN is in Omre NMN + Resveratrol?

500 mg of NMN per two-capsule serving, taken once daily in the morning with food. The product also contains 500 mg of resveratrol and 5 mg of BioPerine in the same serving.

Is Omre NMN vegan?

Yes. Fortune's 2026 roundup named it "Best Vegan NMN Supplement." The capsules are vegetarian and vegan, and the product is listed as gluten-free, soy-free, and dairy-free.

What is Uthever NMN?

Uthever is a branded NMN powder manufactured by Effepharm. It is one of the most widely used NMN raw materials in the supplement industry. Multiple brands use it, so the NMN powder itself is not exclusive to Omre.

Does combining NMN with resveratrol work better?

In one mouse study, the combination raised NAD+ more than NMN alone in certain tissues (Bai et al., 2022). No human trial has tested the combination against NMN alone.

Does BioPerine actually help with resveratrol absorption?

In mice, piperine increased resveratrol exposure by 229% (Johnson et al., 2011). A human pilot study found a non-significant trend at 5 mg piperine (Bailey et al., 2021). The mechanism is plausible; the human evidence is not yet conclusive.

How does Omre compare to GenuinePurity NMN?

GenuinePurity uses 250 mg of liposomal NMN with no resveratrol. Omre uses 500 mg of standard NMN with resveratrol and BioPerine. They are different products for different goals. Our GenuinePurity review covers that product.

Is Omre worth the price?

That depends on whether you value the resveratrol inclusion. At $2.30 per 500 mg of NMN, Omre costs more than most single-ingredient NMN products. If you were going to buy resveratrol separately, the combined price may be competitive.

Who founded Omre?

Omre was founded by Dr. Pedram Kordrostami, a physician. The brand is based in the US with a UK office.

Where can I compare other NMN products?

See our best NMN supplements guide, What Is NMN?, and our own capsule on the YourHealthier NMN product page.